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Combination compounds nutrition
When taking Synofit Premium, it is advised to take it on an empty stomach as possible. As previously reported, this affects the absorption of the ingredients of Synofit Premium (especially Curcumin). If the ingredients of Synofit Premium “get stuck” to the food that is taken at the same time, the ingredients of Synofit Premium are less likely to come into contact with the intestinal wall, therefore reducing the chance of them being absorbed by the body.

Can Synofit Premium be used together with medication?

The Dutch Food and Consumer Product Safety Authority (NVWA) recently published their views on the use of herbal preparations in combination with certain drugs. With regard to Curcumine it was then announced that its use together with sulfasalazine may result in an interaction. Small risks to health can arise here. Do you use sulfasalazine (which is used in intestinal diseases and sometimes also in rheumatism and joint complaints)? Then consult your pharmacist or doctor before you purchase Synofit Premium!
The same applies to the drugs imatinib (used for leukemia), talinolol (a beta blocker) and digoxin (used for heart failure and cardiac arrhythmia).

Are you unsure about the use of Synofit Premium in combination with your medication?

Many customers use the following drugs in combination with Synofit Premium without problems:
• Paracetamol
• Painkillers of the NSAID type (ibuprofen, diclofenac, naproxen, celecoxib, …)
• Gastric protectors (omeprazole, …)
• Painkillers of the Corticosteroid type (tramadol, prednisone, …)
• Blood thinners (acenocoumarol, phenprocoumon, …)
• Blood pressure lowering agents (hydrochlorothiazide, …)
• Cholesterol lowering agents (simvastatin, atorvastatin, …)
• Drugs in diabetics (metformin, …)
• And other drugs such as methotrexate, biologicals, …

If you are taking a drug with levothyroxine (thyroid hormone), you should take Synofit Premium at least 4 hours before or after this medicine. This is because Synofit Premium contains small amounts of calcium and iron, which may affect the way the thyroid gland works if it is taken too quickly after each other.
No further problems are to be expected when using Synofit Premium together with such drugs. In case of doubt or personal questions, you can always contact Synofit (via the contact form). You can of course also contact your pharmacist or doctor.

Can Synofit Premium be combined with other food supplements?

Certain dietary supplements (in part) contain the same substances as Synofit Premium. For example, Vitamin C, Vitamin D3, Vitamin E and Calcium. There are also dietary supplements with only Green-lipped mussel or only Curcumin. The same applies to Boswellia and Blackcurrant leaf. The Green-lipped mussel also naturally contains Glucosamine, Chondroitin, MSM and Omega-3 fatty acids.

It is not harmful to (continue to) use these supplements if you want to use Synofit Premium. However, it is questionable to what extent it is still necessary to continue using these supplements. The latter applies to Green-lipped mussel, Curcumin, Blackcurrant leaf, Boswellia, Vitamin D3, Glucosamine, Chondroitin, MSM and Omega-3 fatty acids (also fish oil). Synofit Premium is a complete supplement of top quality for the joints and in a liquid form, in addition to which your joints need absolutely no additional supplements.

If you use a high dose of Vitamin C or Calcium, for example for resistance or for the bones, it may be useful to continue this parallel to Synofit. The dosage of these nutrients in Synofit Premium is rather low (64% and 2.8% of the daily intake). At the same time, this means that using Synofit Premium in parallel with a high-dose Vitamin C or a Calcium supplement will not rapidly result in an overdose: the risks are near zero.

For some substances in Synofit Premium, the recommended maximum per day is determined:
• Vitamin D: up to 50 μg per day, according to EFSA (source) even 100 μg per day (in Synofit Premium: 5 μg)
• Calcium: up to 2500 mg per day (in Synofit Premium: 22.3 mg)
• Vitamin C: up to 2000 mg per day (in Synofit Premium Liquid: 49 mg / in Synofit Premium Capsules: 51 mg)
• Vitamin E: up to 300 mg per day (in Synofit Premium Liquid: 5 mg / in Synofit Premium Capsules: 4.5 mg)

So, if you use other supplements with Vitamin D, Calcium, Vitamin C or Vitamin E in addition to Synofit Premium, please put all ingredient tables side by side and calculate your daily intake. This way you can check for yourself whether you will come close to a maximum dose per day.
You can also always submit your labels to us, then we can also check whether a (too) high dose of a component is present or whether there are supplements that cannot be used in combination with Synofit Premium.

Synofit Joint Gel

Synofit Joint Gel can be combined with almost every compound. It acts locally and therefore no interaction with medicines, food or dietary supplements will occur.